GENETIC-AF

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Korean Atrial Fibrillation (AF) Network: Genetic Variants for AF Do Not Predict Ablation Success

BACKGROUND Genomewide association studies have identified several loci associated with atrial fibrillation (AF) and have been reportedly associated with response to catheter ablation for AF in patients of European ancestry; however, associations between top susceptibility loci and AF recurrence after ablation have not been examined in Asian populations. We examined whether the top single nucleo...

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Ever since atrial fibrillation (AF) was first recognized in young people (so called "lone" AF) over 4 decades ago, there has been increasing focus on determining the underlying the pathophysiology of the condition. Although lone AF is presumed to be a highly heterogeneous disease, recent studies have identified novel risk factors such as inflammation, oxidative stress, endurance sports and gene...

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AF Termination: the Holy Grail of Persistent AF Ablation?

The optimal catheter ablation approach for longstanding persistent atrial fibrillation (AF) remains elusive despite significant advances made in our understanding of this arrhythmia. A recent systematic review highlighted the significant variation in procedural success rate both within and between techniques, necessitating repeat ablation procedures and anti-arrhythmic drugs to achieve improved...

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Stroke risk in AF: do AF patterns matter?

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, MA, USA; Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, MA, USA; Section of Cardiology, Evans Department of Medicine, Boston University School of Medicine, Framingham, MA, USA; Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA, USA; and Preventive Medicine Section, Whitaker ...

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Western society is at the brink of an atrial fibrillation (AF) explosion. Already AF is the most common sustained arrhythmia worldwide; in the US alone the estimated prevalence in 2010 was between 2.7 to 6.1 million, and this is expected to rise to between 5.6 and 12 million by 2050 [1]. The source of this increase is multifactorial and our current ability to manage the condition is often subop...

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ژورنال

عنوان ژورنال: JACC: Heart Failure

سال: 2019

ISSN: 2213-1779

DOI: 10.1016/j.jchf.2019.05.005